br In the present study
In the present study, salivary ET-1 levels were highly expressed in patients with OSCC, SMF and OL as compared to normal healthy controls. Also, the salivary levels of ET-1 were highly expressed in initial clinical stages of OSCC, implicating the role of ET-1 as a growth factor and tumour initiation factor. It was found that the levels of ET-1 were highly expressed in all stages of SMF, which may indicate its role in oral SCH772984 proliferation and disease progression. Therefore, our results demonstrate potential utility of salivary analysis for ET-1 levels to monitor patients at risk for OSCC.
This study provides the basis for a larger prospective study to determine the critical levels of salivary ET-1 necessary to diagnose and monitor OPMD’s and its potential to undergo malignant transformation. More research in the direction of including other oral potentially malignant disorders will help us to estimate the levels of salivary ET-1, thereby reducing the incidence of OPMDs and consequently preventing oral carcinogenesis.
Disclosure of interest
The authors declare that they have no competing interest.
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Please cite this article in press as: Ankita K, et al. Assessment of salivary endothelin-1 in patients with leukoplakia, submucous fibrosis, oral cancer and healthy individuals – a comparative study. J Stomatol Oral Maxillofac Surg (2019), https://doi.org/10.1016/ j.jormas.2019.02.024
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Please cite this article in press as: Ankita K, et al. Assessment of salivary endothelin-1 in patients with leukoplakia, submucous fibrosis, oral cancer and healthy individuals – a comparative study. J Stomatol Oral Maxillofac Surg (2019), https://doi.org/10.1016/ j.jormas.2019.02.024 Clinical Biomechanics 69 (2019) 28–33
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Assessment of the Mini-Balance Evaluation Systems Test, Timed Up and Go T test, and body sway test between cancer survivors and healthy participants
Shinichiro Morishitaa, , Ryo Hirabayashia, Atsuhiro Tsubakia, Osamu Aokib, Jack B. Fuc, Hideaki Onishia, Tetsuya Tsujid
a Institute for Human Movement and Medical Sciences, Niigata University of Health and Welfare, Shimami-cho 1398, Kita-ku, Niigata City 950-3198, Japan
b Faculty of Rehabilitation, Shijonawate Gakuen University, Osaka 574-0011, Japan
c Department of Palliative, Rehabilitation and Integrative Medicine, University of Texas MD Anderson Cancer Center, Houston, TX, USA
d Department of Rehabilitation Medicine, Keio University School of Medicine, Tokyo, Japan
Mini-Balance Evaluation Systems Test
Timed Up and Go
Background: Cancer survivors experience late and long-term eﬀects of treatment; also, the disease itself might be responsible for persisting functional impairments. The purpose of this study was to investigate muscle strength, balance function using the Mini-Balance Evaluation Systems Test and Timed Up and Go test with single and cognitive dual tasks and body sway in breast cancer survivors and healthy women and non-breast cancer sur-vivors and healthy participants.